If you are interested, try this:
1. In Usine I load the Remote Channel Sender plugin from VSTforx into the rack that I want to manipulate (for example with a 32 bit filter plugin).

2. In Reaper I load the VSTforx plugin and assign the Remote Channel Receiver to it's output. In the same chain I add my filter plugin. The third plugin in this chain is another Remote Channel Sender plugin.

3. Back in Usine I need another VSTforx plugin to receive the Remote Channel from Reaper and redirect it to the rack output.
4. Now, in Reaper the master volume can be muted. The sound is now being generated in Usine, filtered in Reaper and sent from Usine to the connected audio interface.
Further info: www.reaper.fm, www.vstforx.de, http://www.vstforx.de/index.php/product ... otechannel


